The patient was sick. On death’s door kind of sick. They were a nice person – treating all the hospital staff with respect. Saying “please” and “thank you.” Cracking jokes even though they were ill. They were articulate. Earlier in their hospital stay we’d discussed God. They believed strongly in the power of God. The patient explained that they were at peace with their life and were ready to join God whenever he called.

Then one night the nurse found the patient completely naked in their room. At that time, the patient couldn’t remember their name. The nurse was able to redirect them, remind them of their name, and put them back to bed. They were embarrassed by the events the next morning. In the morning, they seemed to still understand what was happening around them.

The next night they became confused again. But, this time, they weren’t better by morning. As the days unfolded, they were usually able to tell me their name. They’d lost track of why they were in the hospital or what the plan for the day was. They didn’t know the month or the year. At times they seemed more lucid and at other times they were so confused that they believed they were on a business trip. Occasionally they were angry. But, more often, they looked scared. They were easily frightened because they didn’t know where they were or what was happening to them.

This patient was a classic example of delirium. Delirium is a state of confusion that waxes and wanes. It occurs because of the unfamiliarity of the hospital setting, the disruptive nature of hospital activity, and the stress of being ill.  Every patient in the hospital is at risk of developing delirium during their stay. Some people are at greater risk of delirium – elderly people, severely ill people, and people with underlying brain illness.

Delirium is complex from a medical standpoint. We try to prevent it but everything about the hospital promotes delirium – from frequent sleep disruptions to the unfamiliar setting and faces of the hospital. Preventing delirium involves encouraging family members to visit, minimizing overnight wake ups for medical care (vitals, blood draws, meds, etc.), and frequently reminding patients of where they are and the date. We try hard to ensure lights are off at night and lights are on during the day (and window shades open). Despite precautions, delirium can still develop. The challenge is that we have no good treatment for it. Overcoming delirium involves the same strategies as preventing it and treating the illness that brought patients to the hospital in the first place. Another difficult aspect of delirium is managing it when it causes patients to become agitated.

When patients are lost in delirium they don’t act as they normally would. They are in a state of confusion. They may scream and cry not because they are in physical distress but because they don’t understand what is happening. They might fight hospital staff or try to run away. They might become dangerous to staff or other patients. They might refuse the medical care they need to get better. Sometimes to keep a delirious patient and staff safe we need to use sedating medications. But sedating medications can prolong delirium. It’s a tricky situation.

Delirium is one of those conditions that takes up a lot of my time as a physician and consumes nursing time but is little-known among people who don’t work in healthcare. In the short term, it can negatively impact patients by making it difficult to care for them. In the long term, it may impact patients’ cognition.  

Everyone should know about delirium because the best way to prevent delirium has nothing to do with medicine. Delirium is most successfully prevented by having family/friends at bedside. Patients who have frequent family/friend visits (ideally daily for multiple hours) while in the hospital are less likely to develop delirium. The reason family/friends are so important is that they are familiar faces. They can help patients keep track of night and day. Family/friends help keep patients’ minds engaged in conversation, games, and other shared activities. Engaging the mind helps keep it from getting lost in delirium.

In the US, it is fascinating how many patients don’t have family members or friends visit while they’re in the hospital. There are many reasons for this, but two important ones are the American focus on independence and our geographic distance from relatives. Many Americans can’t help that they live hours from their family (and even their friends). But, in an era of electronic connectivity, don’t forget that your loved ones need you. Try a voice or video call. Call or visit even if your loved one says they’re fine. Your support might be the reason your loved one remembers their name the entire time they’re in the hospital. And that, though seemingly small, might make a world of difference in their recovery.